Below are some potential notable starts being made by drivers this weekend. Notable meaning they will be tied with a driver in number of starts made in that specific series, or the number of starts being made is a significant number that they are reaching in their specific race this weekend at Circuit of the Americas. Rankings reflect the all-time starts list for that series.
(The image above each series is the driver I find having the most notable start this weekend)
*This will be updated after qualifying for each race if a driver does not make the race.

Xfinity Series Starts
Jeremy Clements: 500th start! Ranks 4th
Riley Herbst: 176th start ties Cole Custer, ranks 87th
Anthony Alfredo: 121st start ties Dave Blaney, ranks 139th
Josh Bilicki: 110th start ties Ricky Stenhouse Jr., ranks 159th
Matt DiBenedetto: 100th start! Ranks 173rd
William Byron: 42nd start ties Rusty Wallace & Travis Pastrana, ranks 310th
Baltazar Leguizamon: 1st start!

Cup Series Starts
Brad Keselowski: 560th start ties Cale Yarborough, ranks 38th
Chase Elliott: 325th start!
Ty Dillon: 248th start ties Matt DiBenedetto, ranks 121st
Tyler Reddick: 185th start ties Tim Richmond, ranks 159th
Cody Ware: 109th start ties Harrison Burton, ranks 217th
Josh Berry: 51st start ties Ralph Earnhardt, ranks 312th
Connor Zilisch: 1st start!