Below are some potential notable starts being made by drivers this weekend. Notable meaning they will be tied with a driver in number of starts made in that specific series, or the number of starts being made is a significant number that they are reaching in their specific race this weekend at Darlington Raceway. Rankings reflect the all-time starts list for that series.
(The image above each series is the driver I find having the most notable start this weekend)
*This will be updated after qualifying for each race if a driver does not make the race.

Xfinity Series Starts
Ryan Sieg: 375th start! Ranks 14th
Brennan Poole: 165th start ties Ty Dillon, ranks 95th
Ryan Ellis: 139th start ties Noah Gragson, ranks 116th
Sam Mayer: 125th start!
Austin Hill: 122nd start ties Aric Almirola & Parker Kligerman, ranks 139th
Sheldon Creed: 111th start ties John Hunter Nemechek, ranks 157th
Chase Elliott: 86th start ties Bobby Hamilton, Chase Briscoe & Davey Allison, ranks 199th
Daniel Dye: 20th start ties Donnie Allison, ranks 428th
Dean Thompson & Nick Leitz: 10th start!

Cup Series Starts
Denny Hamlin: 694th start ties Martin Truex Jr., ranks 24th
Ryan Blaney: 350th start!
Alex Bowman: 333rd start ties David Gilliland, ranks 90th
Bubba Wallace: 263rd start ties Greg Sacks, ranks 116th
Cole Custer: 125th start!
Noah Gragson: 83rd start ties Justin Allgaier, ranks 250th
Josh Berry: 56th start ties Buckshot Jones, ranks 302nd