Below are some potential notable starts being made by drivers this weekend. Notable meaning they will be tied with a driver in number of starts made in that specific series, or the number of starts being made is a significant number that they are reaching in their specific race this weekend at Pocono Raceway. Rankings reflect the all-time starts list for that series.
(The image above each series is the driver I find having the most notable start this weekend)

*This will be updated after qualifying for each race if a driver does not make the race.

Tyler Ankrum makes milestone Truck start number 150 this weekend at Pocono. Image credit: @BMR_NASCAR X Page

Truck Series Starts

Tyler Ankrum: 150th start! Ranks 26th

Corey Heim: 78th start ties Aric Almirola, ranks 74th

Chandler Smith: 76th start ties Derek Kraus, Sheldon Creed & Ty Dillon, ranks 80th

Jack Wood: 75th start! Ranks 84th

Matt Mills: 60th start ties Carl Edwards & Scott Riggs, ranks 113th

Layne Riggs: 43rd start ties Matt DiBenedetto, ranks 170th

Connor Mosack: 25th start! Ties Jamie McMurray & Mark Martin, ranks 262nd

Frankie Muniz & Toni Breidinger: 18th start ties Chase Elliott, ranks 314th

Ryan Ellis will make his 147th career Xfinity start this weekend which ties him with 2x Xfinity Series Champion Dale Earnhardt Jr. for 111th most all-time. Image credit: @DGMRacingFL X Page

Xfinity Series Starts

Ryan Ellis: 147th start ties Buckshot Jones & Dale Earnhardt Jr., ranks 111th

Sam Mayer: 133rd start ties Austin Cindric, ranks 124th

Sheldon Creed: 119th start ties Kyle Larson, ranks 145th

Kyle Sieg: 97th start ties Josh Berry, ranks 177th

Chase Elliott: 87th start ties Chase Briscoe, ranks 202nd

Patrick Emerling: 57th start ties Alex Bowman & Ernie Irvan, ranks 257th

Leland Honeyman: 50th start!

Carson Kvapil: 25th start!

Logan Bearden: 10th start!

This weekend Brad Keselowski will tie NASCAR Legend and Hall of Famer, David Pearson by making his 574th career Cup start. Image credit: @RFKRacing X Page

Cup Series Starts

Brad Keselowski: 574th start ties David Pearson, ranks 37th

Austin Dillon: 425th start! Ranks 67th

Todd Gilliland: 125th start!

Carson Hocevar & Zane Smith: 62nd start ties Glen Wood, ranks 292nd

Riley Herbst: 25th start!