Below are some potential notable starts being made by drivers this weekend. Notable meaning they will be tied with a driver in number of starts made in that specific series, or the number of starts being made is a significant number that they are reaching in their specific race this weekend at Darlington Raceway/Portland International Raceway. Rankings reflect the all-time starts list for that series.
(The image above each series is the driver I find having the most notable start this weekend)
*This will be updated after qualifying for each race if a driver does not make the race.

Spencer Body makes his 150th career Truck Series start this weekend at Darlington. Image credit: @SpencerBoyd X Page
Truck Series Starts
Spencer Body: 150th start! Ranks 27th
Timmy Hill: 117th start ties Ross Chastain, ranks 45th
Ty Majeski: 108th start ties Ryan Sieg, ranks 51st
Corey Heim: 83rd start ties Greg Biffle, ranks 67th
Chandler Smith: 81st start ties Carson Hocevar, ranks 69th
Daniel Hemric, Jake Garcia & Rajah Caruth: 69th start ties Hailie Deegan & Robert Pressley, ranks 98th
Matt Mills: 65th start ties Boris Said & Steve Park, ranks 107th
Kaden Honeycutt: 53rd start ties Justin Haley, ranks 139th
Trevor Bayne: 10th start!

This weekend at Portland Jeb Burton makes milestone start number 200 in the Xfinity Series. Image credit @JARnascar X Page
Xfinity Series Starts
Ryan Sieg: 392nd start ties Elton Sawyer, ranks 13th
Jeb Burton: 200th start! Ranks 73rd
Ryan Ellis: 156th start ties Austin Dillon, ranks 106th
Sam Mayer: 142nd start ties Ricky Craven, ranks 116th
Sheldon Creed: 128th start ties Aric Almirola & Harry Gant, ranks 135th
Matt DiBenedetto: 122nd start ties Parker Kligerman, ranks 143rd
Blaine Perkins, Harrison Burton & Sammy Smith: 100th start! Ranks 175th
Parker Retlzaff: 99th start ties Tyler Reddick, ranks 178th
Christian Eckes: 25th start! Ranks 399th
Joey Hand, Takuma Koga & Will Brown: 1st start!

Alex Bowman ties NASCAR Hall of Famer and 2x Cup Series Champion “Gentleman” Ned Jarrett on the all-time Cup starts list by making his 352nd career Cup start. Image credit: @TeamHendrick X Page
Cup Series Starts
Brad Keselowski: 584th start ties Jamie McMurray, ranks 35th
A.J. Allmendinger: 473rd start ties Dave Blaney, ranks 55th
Kyle Larson: 393rd start ties J.J. Yeley, ranks 73rd
Alex Bowman: 352nd start ties Ned Jarrett, ranks 84th
Ross Chastain: 250th start! Ranks 122nd
Christopher Bell: 207th start ties Alan Kulwicki, ranks 144th
Josh Berry: 75th start! Ranks 268th